Galectins are carbohydrate-binding proteins that are involved in many physiological
functions, such as inflammation, immune responses, cell migration, autophagy and …

Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Cell surface transmembrane receptors often form nanometer-to micrometer-scale clusters to
initiate signal transduction in response to environmental cues. Extracellular ligand …

Galectin-3 is a versatile protein orchestrating several physiological and pathophysiological
processes in the human body. In the last decade, considerable interest in galectin-3 has …

In obesity, macrophages and other immune cells accumulate in insulin target tissues,
promoting a chronic inflammatory state and insulin resistance. Galectin-3 (Gal3), a lectin …

Galectin-3 is a beta-galactoside-binding mammalian lectin and part of the 15 member
galectin family that are evolutionarily highly conserved. It is the only chimeric protein with a …

Galectins are a family of proteins that bind to specific glycans thereby deciphering the
information captured within the glycome. In the last two decades, several galectin family …

Galectins are a family of widely expressed β-galactoside-binding lectins in metazoans. The
15 mammalian galectins have either one or two conserved carbohydrate recognition …

Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …