Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

MA Fernandez-Yague, SA Abbah, L McNamara… - Advanced drug delivery …, 2015 - Elsevier
The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

Tuning the biomimetic behavior of scaffolds for regenerative medicine through surface modifications

NR Richbourg, NA Peppas… - Journal of tissue …, 2019 - Wiley Online Library
Tissue engineering and regenerative medicine rely extensively on biomaterial scaffolds to
support cell adhesion, proliferation, and differentiation physically and chemically in vitro and …

Advancements and frontiers in nano-based 3D and 4D scaffolds for bone and cartilage tissue engineering

M Qasim, DS Chae, NY Lee - International journal of nanomedicine, 2019 - Taylor & Francis
Given the enormous increase in the risks of bone and cartilage defects with the rise in the
aging population, the current treatments available are insufficient for handling this burden …

Effect of sterilization methods on electrospun poly (lactic acid)(PLA) fiber alignment for biomedical applications

TAM Valente, DM Silva, PS Gomes… - … applied materials & …, 2016 - ACS Publications
Medically approved sterility methods should be a major concern when develo** a
polymeric scaffold, mainly when commercialization is envisaged. In the present work, poly …

Electrospun biodegradable nanofibers scaffolds for bone tissue engineering

R Khajavi, M Abbasipour… - Journal of Applied …, 2016 - Wiley Online Library
Many polymeric materials have been developed and introduced for bone regeneration.
Especially, their nanofibrous forms are mostly applied for artificial extracellular matrices …

Regenerative medicine and drug delivery: Progress via electrospun biomaterials

M Doostmohammadi, H Forootanfar… - Materials Science and …, 2020 - Elsevier
Worldwide research on electrospinning enabled it as a versatile technique for producing
nanofibers with specified physio-chemical characteristics suitable for diverse biomedical …

Osteoinductive fibrous scaffolds of biopolymer/mesoporous bioactive glass nanocarriers with excellent bioactivity and long-term delivery of osteogenic drug

A El-Fiqi, JH Kim, HW Kim - ACS applied materials & interfaces, 2015 - ACS Publications
Designing scaffolds with bioactive composition and long-term drug delivery capacity is a
promising method to improve the therapeutic efficacy in bone regeneration. Herein …

[HTML][HTML] Therapeutically relevant aspects in bone repair and regeneration

RA Perez, SJ Seo, JE Won, EJ Lee, JH Jang… - Materials Today, 2015 - Elsevier
Over the past few years, attention has been focused on the therapeutic roles in designing
bone scaffolds for successful repair and regeneration. Indeed, biologically dynamic events …

Therapeutic-designed electrospun bone scaffolds: mesoporous bioactive nanocarriers in hollow fiber composites to sequentially deliver dual growth factors

MS Kang, JH Kim, RK Singh, JH Jang, HW Kim - Acta biomaterialia, 2015 - Elsevier
A novel therapeutic design of nanofibrous scaffolds, holding a capacity to load and deliver
dual growth factors, that targets bone regeneration is proposed. Mesoporous bioactive glass …

Biodegradable and biocompatible systems based on hydroxyapatite nanoparticles

P Turon, LJ Del Valle, C Alemán, J Puiggalí - Applied Sciences, 2017 - mdpi.com
Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to
their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development of …