Fc receptors (FcRs) belong to the ITAM-associated receptor family. FcRs control the humoral
and innate immunity which are essential for appropriate responses to infections and …

Fc receptors (FcRs) belong to the ITAM-associated receptor family. FcRs control the humoral
and innate immunity which are essential for appropriate responses to infections and …

Antibody-dependent enhancement (ADE) of infectious disease is a phenomenon whereby
host antibodies increase the severity of an infection. It is well established in viral infections …

FcγRs have been the focus of extensive research due to their key role linking innate and
humoral immunity and their implication in both inflammatory and infectious disease. Within …

Tumor‐targeting monoclonal antibodies are available for a number of cancer cell types
(over) expressing the corresponding tumor antigens. Such antibodies can limit tumor …

The function of the low-affinity IgG-receptor FcγRIIIb (CD16b), which is uniquely and
abundantly expressed on human granulocytes, is not clear. Unlike the other Fcγ receptors …

Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE) that
occurs in about half of patients. LN is characterized by glomerular deposition of immune …

Fc-gamma receptors (FcγR) are the cellular receptors for Immunoglobulin G (IgG). Upon
binding of complexed IgG, FcγRs can trigger various cellular immune effector functions …

Tissue-resident macrophages in the spleen play a major role in the clearance of
immunoglobulin G (IgG)–opsonized blood cells, as occurs in immune thrombocytopenia …

Simple Summary Immunotherapy aims to engage various immune cells in the elimination of
cancer cells. Neutrophils are the most abundant leukocytes in the circulation and have …