Adaptive optics for high-resolution imaging

KM Hampson, R Turcotte, DT Miller… - Nature Reviews …, 2021 - nature.com
Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …

[HTML][HTML] Vision science and adaptive optics, the state of the field

S Marcos, JS Werner, SA Burns, WH Merigan, P Artal… - Vision research, 2017 - Elsevier
Adaptive optics is a relatively new field, yet it is spreading rapidly and allows new questions
to be asked about how the visual system is organized. The editors of this feature issue have …

Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics

RR Iyer, JE Sorrells, L Yang, EJ Chaney… - Scientific reports, 2022 - nature.com
Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet,
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …

From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation

G Palczewska, M Wojtkowski, K Palczewski - Progress in retinal and eye …, 2023 - Elsevier
The eye is an ideal organ for imaging by a multi-photon excitation approach, because ocular
tissues such as the sclera, cornea, lens and neurosensory retina, are highly transparent to …

Computational optical coherence tomography

YZ Liu, FA South, Y Xu, PS Carney… - Biomedical optics …, 2017 - opg.optica.org
Optical coherence tomography (OCT) has become an important imaging modality with
numerous biomedical applications. Challenges in high-speed, high-resolution, volumetric …

Sensorless adaptive optics multimodal en-face small animal retinal imaging

DJ Wahl, R Ng, MJ Ju, Y Jian… - Biomedical Optics Express, 2018 - opg.optica.org
Vision researchers often use small animals due to the availability of many transgenic strains
that model human diseases or express biomarkers. Adaptive optics (AO) enables non …

[HTML][HTML] Two-photon imaging of the mammalian retina with ultrafast pulsing laser

G Palczewska, P Stremplewski, S Suh, N Alexander… - JCI insight, 2018 - ncbi.nlm.nih.gov
Noninvasive imaging of visual system components in vivo is critical for understanding the
causal mechanisms of retinal diseases and for develo** therapies for their treatment …

Wavefront correction in two-photon microscopy with a multi-actuator adaptive lens

JM Bueno, M Skorsetz, S Bonora, P Artal - Optics express, 2018 - opg.optica.org
A multi-actuator adaptive lens (AL) was incorporated into a multi-photon (MP) microscope to
improve the quality of images of thick samples. Through a hill-climbing procedure the AL …

Volumetric fluorescence retinal imaging in vivo over a 30-degree field of view by oblique scanning laser ophthalmoscopy (oSLO)

L Zhang, W Song, D Shao, S Zhang, M Desai… - Biomedical Optics …, 2017 - opg.optica.org
While fluorescent contrast is widely used in ophthalmology, three-dimensional (3D)
fluorescence retinal imaging over a large field of view (FOV) has been challenging. In this …

Adaptive optics in the mouse eye: wavefront sensing based vs. image-guided aberration correction

DJ Wahl, P Zhang, J Mocci, M Quintavalla… - Biomedical Optics …, 2019 - opg.optica.org
Adaptive Optics (AO) is required to achieve diffraction limited resolution in many real-life
imaging applications in biology and medicine. AO is essential to guarantee high fidelity …