Treatment avenues for age-related macular degeneration: Breakthroughs and bottlenecks

P Kumbhar, K Kolekar, S Vishwas, P Shetti… - Ageing Research …, 2024 - Elsevier
Age-related macular degeneration (AMD) is a significant factor contributing to serious vision
loss in adults above 50. The presence of posterior segment barriers serves as chief …

Applications of cellulose-based materials in sustained drug delivery systems

B Sun, M Zhang, J Shen, Z He… - Current medicinal …, 2019 - ingentaconnect.com
Bio-compatible, bio-degradable, and bio-available excipients are of critical interest for drug
delivery systems. Cellulose and its derivative-based excipients have been well studied due …

Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection

JJ López-Cano… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The development of ophthalmic formulations able to deliver hydrophilic and
hydrophobic drugs to the inner structures of the eye and restore the preocular tear film has …

[HTML][HTML] Ocular therapeutics and molecular delivery strategies for neovascular age-related macular degeneration (Namd)

A Sarkar, V Junnuthula, S Dyawanapelly - International Journal of …, 2021 - mdpi.com
Age-related macular degeneration (AMD) is the leading cause of vision loss in geriatric
population. Intravitreal (IVT) injections are popular clinical option. Biologics and small …

Multifunctional nano-in-micro delivery systems for targeted therapy in fundus neovascularization diseases

X Liu, K Huang, F Zhang, G Huang, L Wang… - Journal of …, 2024 - Springer
Fundus neovascularization diseases are a series of blinding eye diseases that seriously
impair vision worldwide. Currently, the means of treating these diseases in clinical practice …

Therapeutic potential of curcumin in major retinal pathologies

KV Peddada, A Brown, V Verma… - International …, 2019 - Springer
Purpose The retina is continually exposed to free radicals from its rich blood supply,
numerous mitochondria, and photons of light which strike its surface. Most pathological …

Emerging innovations in nano-enabled therapy against age-related macular degeneration: A paradigm shift

SK Dubey, R Pradhan, S Hejmady, G Singhvi… - International Journal of …, 2021 - Elsevier
Age-related macular degeneration (AMD), a degenerative eye disease, is the major cause of
irreversible loss of vision among individuals aged 50 and older. Both genetic and …

Nanodiagnostics and Nanotherapeutics for age-related macular degeneration

A Sarkar, S Dyawanapelly - Journal of Controlled Release, 2021 - Elsevier
Age-related macular degeneration (AMD) is the third leading cause worldwide blindness
that causes permanent central vision impairment in older people. Over the past few years …

Potential application of liposomal nanodevices for non-cancer diseases: An update on design, characterization and biopharmaceutical evaluation

F Bayat, R Hosseinpour-Moghadam, F Mehryab… - Advances in colloid and …, 2020 - Elsevier
Liposomes, lipid-based vesicular systems, have attracted major interest as a means to
improve drug delivery to various organs and tissues in the human body. Recent literature …

Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN

Q Xu, S Cao, S Rajapakse, JA Matsubara - Lipids in health and disease, 2018 - Springer
Rationale Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly. Due to its complex etiology, current treatments have been …