The SOS response of bacteria is a global regulatory network targeted at addressing DNA
damage. Governed by the products of the lexA and recA genes, it co-ordinates a …

The rise in fluorescence-based imaging techniques over the past 3 decades has improved
the ability of researchers to scrutinize live cell biology at increased spatial and temporal …

All organisms possess a diverse set of genetic programs that are used to alter cellular
physiology in response to environmental cues. The gram-negative bacterium Escherichia …

The RecA protein orchestrates the cellular response to DNA damage via its multiple roles in
the bacterial SOS response. Lack of tools that provide unambiguous access to the various …

Homologous recombination (HR) is a fundamental process common to all species. HR aims
to faithfully repair DNA double strand breaks. HR involves the formation of nucleoprotein …

The genetics and biochemistry of genetic recombination in E. coli has been studied for over
four decades and provides a useful model system to understand recombination in other …

RecA is central to maintaining genome integrity in bacterial cells. Despite the near-
ubiquitous conservation of RecA in eubacteria, the pathways that facilitate RecA loading and …

RecA plays a key role in homologous recombination, the induction of the DNA damage
response through LexA cleavage and the activity of error-prone polymerase in Escherichia …

Homologous recombination is an ubiquitous process that shapes genomes and repairs DNA
damage. The reaction is classically divided into three phases: presynaptic, synaptic, and …

This study shows that the expression of yjcC, an in vivo expression (IVE) gene, and the
stress response regulatory genes soxR, soxS, and rpoS are paraquat inducible in Klebsiella …