Label-free functional analysis of root-associated microbes with dynamic quantitative oblique back-illumination microscopy

C Filan, M Green, A Diering, MT Cicerone… - Scientific Reports, 2024 - nature.com
The increasing global demand for food, coupled with concerns about the environmental
impact of synthetic fertilizers, underscores the urgency of develo** sustainable agricultural …

Acetic acid enabled nuclear contrast enhancement in epi-mode quantitative phase imaging

Z Guang, A Jacobs, PC Costa, Z Li… - Journal of Biomedical …, 2025 - spiedigitallibrary.org
Significance The acetowhitening effect of acetic acid (AA) enhances light scattering of cell
nuclei, an effect that has been widely leveraged to facilitate tissue inspection for (pre) …

Experimental assessment of the optical transfer function for quantitative oblique back illumination microscopy (qOBM)

Z Li, P Casteleiro Costa, C Serafini, S Bharadwaj… - Optics …, 2025 - opg.optica.org
Quantitative oblique back illumination microscopy (qOBM) is a recently developed imaging
technique that enables 3D quantitative phase imaging (QPI) and refractive index (RI) …

Revealing 3D cancer tissue structures using holotomography and virtual hematoxylin and eosin staining via deep learning

J Park, SJ Shin, M Kim, G Kim, H Cho, D Ryu, D Ahn… - bioRxiv, 2023 - biorxiv.org
In standard histopathology, hematoxylin and eosin (H&E) staining stands as a pivotal tool for
cancer tissue analysis. However, this method is limited to two-dimensional (2D) analysis or …

Real-time in-vivo volumetric quantitative phase imaging with a compact handheld probe

Z Guang, PC Costa, Z Li, J Lerner… - … Phase Imaging X, 2024 - spiedigitallibrary.org
Quantitative phase imaging (QPI) offers label-free access to refractive index information of
biological samples, which can achieve nanometer-level optical-path-length sensitivity with …

Neural network assisted fast refractive index tomography in thick tissues with quantitative oblique back-illumination microscopy

Z Li, PC Costa, Z Guang… - Label-free Biomedical …, 2024 - spiedigitallibrary.org
Quantitative phase imaging (QPI) has emerged as a valuable method in biomedical
research by providing label-free, high-resolution phase distribution of transparent cells and …

Experimental assessment of the optical transfer function for quantitative oblique back-illumination microscopy

Z Li, C Filan, Z Guang, PC Costa… - Label-free Biomedical …, 2024 - spiedigitallibrary.org
Quantitative oblique back illumination microscopy (qOBM) is a recently developed phase
imaging modality that enables 3D quantitative phase imaging and refractive index (RI) …

Multimodal fluorescence microscopy and 3D quantitative phase imaging/refractive index tomography in thick tissue samples

Z Li, Z Guang, PC Costa, C Filan… - … Phase Imaging X, 2024 - spiedigitallibrary.org
Phase imaging and fluorescence microscopy provide valuable complementary information,
and individually form the basis for a significant portion of the routing biological and …

Epi-mode 3D quantitative phase imaging with quantitative oblique back illumination microcopy (qOBM): recent advances in functional and dynamic contrast

FE Robles - Three-Dimensional and Multidimensional …, 2024 - spiedigitallibrary.org
Quantitative oblique back illumination microscopy (qOBM) enables 3D quantitative phase
imaging (QPI) and refractive index tomography (ie, optical diffraction tomography, or ODT) in …