Central nervous system (CNS) lesions become surrounded by neuroprotective borders of
newly proliferated reactive astrocytes; however, fundamental features of these cells are …

As a population of homogeneous cells with both self-renewal and differentiation potential,
stem cell pools are highly compartmentalized and contain distinct subsets that exhibit stable …

In a develo** embryo, formation of tissues and organs is remarkably precise in both time
and space. Through cell-cell interactions, neighboring progenitors coordinate their activities …

Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …

The human body function requires crosstalk between different tissues. An essential crosstalk
is in the neuromusculoskeletal (NMS) axis involving neural, muscular, and skeletal tissues …

Various mature tissue-resident cells exhibit progenitor characteristics following injury.
However, the existence of endogenous stem cells with multiple lineage potentials in the …

Regenerative capacities and strategies vary dramatically across animals, as well as
between cell types, organs, and with age. In recent years, high-throughput single-cell …

Ependymal cells lining the central canal of the spinal cord play a crucial role in providing a
physical barrier and in the circulation of cerebrospinal fluid. These cells express the FOXJ1 …

A growing body of evidence indicates intra-and inter-regional heterogeneity of astrocytes in
the brain. However, because of a lack of an efficient method for isolating astrocytes from the …

Spinal cord injury (SCI) is a medical condition affecting~ 2.5–4 million people worldwide.
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …