The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Plastically compressed dense collagen (DC) gels mimic the microstructural, mechanical,
and biological properties of native osteoid. This study investigated the effect of hybridizing …

Fiber-based scaffolds produced by textile manufacturing technology offer versatile materials
for tissue engineering applications since a wide range of crucial scaffold parameters …

Recent advancements in 3D bioprinting have led to the fabrication of more complex, more
precise, and larger printed tissue constructs. As the field continues to advance, it is critical to …

The creation of large, volumetric tissue-engineered constructs has long been hindered due
to the lack of effective vascularization strategies. Recently, 3D printing has emerged as a …

The adipose tissue is a crucial endocrine organ that coordinates with other organs, playing a
key role in metabolic regulation. However, it remains challenging to recreate the morphology …

The intercellular signaling mechanisms among a transplanted cell population are largely
determined by the cell population itself as well as the surrounding environment. Changes in …

Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which are vital
for the regulation of bone formation and resorption. ECM stiffness and cell seeding density …

Gelatin methacryloyl (GelMA) has been widely studied as a biomaterial for tissue
engineering. Most studies focus on mammalian gelatin, but certain factors, such as …