Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Artificial intelligence-enhanced electrocardiography in cardiovascular disease management

KC Siontis, PA Noseworthy, ZI Attia… - Nature Reviews …, 2021 - nature.com
The application of artificial intelligence (AI) to the electrocardiogram (ECG), a ubiquitous and
standardized test, is an example of the ongoing transformative effect of AI on cardiovascular …

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

Predictors of COVID‐19 severity: a literature review

B Gallo Marin, G Aghagoli, K Lavine… - Reviews in medical …, 2021 - Wiley Online Library
Summary The coronavirus disease 2019 (COVID‐19) pandemic is a rapidly evolving global
emergency that continues to strain healthcare systems. Emerging research describes a …

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

Extrapulmonary manifestations of COVID-19

A Gupta, MV Madhavan, K Sehgal, N Nair… - Nature medicine, 2020 - nature.com
Although COVID-19 is most well known for causing substantial respiratory pathology, it can
also result in several extrapulmonary manifestations. These conditions include thrombotic …

Prevalence and impact of myocardial injury in patients hospitalized with COVID-19 infection

A Lala, KW Johnson, JL Januzzi, AJ Russak… - Journal of the American …, 2020 - jacc.org
Background The degree of myocardial injury, as reflected by troponin elevation, and
associated outcomes among US hospitalized patients with coronavirus disease-2019 …

Cardiac Troponin for Assessment of Myocardial Injury in COVID-19: JACC Review Topic of the Week

Y Sandoval, JL Januzzi Jr, AS Jaffe - Journal of the American college of …, 2020 - jacc.org
Increases in cardiac troponin indicative of myocardial injury are common in patients with
coronavirus disease-2019 (COVID-19) and are associated with adverse outcomes such as …

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: a case series

AV Rapkiewicz, X Mai, SE Carsons, S Pittaluga… - …, 2020 - thelancet.com
Background There is increasing recognition of a prothrombotic state in COVID-19. Post-
mortem examination can provide important mechanistic insights. Methods We present a …

Mechanisms in endocrinology: vitamin D and COVID-19

JP Bilezikian, D Bikle, M Hewison… - European journal of …, 2020 - academic.oup.com
The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …