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The lifespan human connectome project in aging: an overview
SY Bookheimer, DH Salat, M Terpstra, BM Ances… - Neuroimage, 2019 - Elsevier
Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …
functional connectivity in a large sample of healthy young adults using improved methods of …
Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease
R De Flores, R La Joie, G Chételat - Neuroscience, 2015 - Elsevier
Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …
Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of …
RNM Saleh, M Hornberger, CW Ritchie… - Alzheimer's research & …, 2023 - Springer
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …
consequences of estrogen decline during menopause accelerate neuropathology in …
[HTML][HTML] A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI
JE Iglesias, JC Augustinack, K Nguyen, CM Player… - Neuroimage, 2015 - Elsevier
Automated analysis of MRI data of the subregions of the hippocampus requires
computational atlases built at a higher resolution than those that are typically used in current …
computational atlases built at a higher resolution than those that are typically used in current …
Longitudinal changes in cortical thickness associated with normal aging
M Thambisetty, J Wan, A Carass, Y An, JL Prince… - Neuroimage, 2010 - Elsevier
Imaging studies of anatomic changes in regional gray matter volumes and cortical thickness
have documented age effects in many brain regions, but the majority of such studies have …
have documented age effects in many brain regions, but the majority of such studies have …
Automated segmentation of hippocampal subfields from ultra‐high resolution in vivo MRI
K Van Leemput, A Bakkour, T Benner, G Wiggins… - …, 2009 - Wiley Online Library
Recent developments in MRI data acquisition technology are starting to yield images that
show anatomical features of the hippocampal formation at an unprecedented level of detail …
show anatomical features of the hippocampal formation at an unprecedented level of detail …
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments
EM Reiman, J Langbaum, AS Fleisher… - Journal of …, 2011 - content.iospress.com
There is an urgent need to find effective presymptomatic Alzheimer's disease (AD)
treatments that reduce the risk of AD symptoms or prevent them completely. It currently takes …
treatments that reduce the risk of AD symptoms or prevent them completely. It currently takes …
Association of docosahexaenoic acid supplementation with Alzheimer disease stage in apolipoprotein E ε4 carriers: a review
HN Yassine, MN Braskie, WJ Mack, KJ Castor… - JAMA …, 2017 - jamanetwork.com
Importance The apolipoprotein E ε4 (APOE4) allele identifies a unique population that is at
significant risk for develo** Alzheimer disease (AD). Docosahexaenoic acid (DHA) is an …
significant risk for develo** Alzheimer disease (AD). Docosahexaenoic acid (DHA) is an …
Bayesian longitudinal segmentation of hippocampal substructures in brain MRI using subject-specific atlases
JE Iglesias, K Van Leemput, J Augustinack, R Insausti… - Neuroimage, 2016 - Elsevier
The hippocampal formation is a complex, heterogeneous structure that consists of a number
of distinct, interacting subregions. Atrophy of these subregions is implied in a variety of …
of distinct, interacting subregions. Atrophy of these subregions is implied in a variety of …
Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease
SG Potkin, G Guffanti, A Lakatos, JA Turner, F Kruggel… - PloS one, 2009 - journals.plos.org
Background With the exception of APOE ε4 allele, the common genetic risk factors for
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings We completed a …
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings We completed a …