Monocyte-derived tumor-associated macrophages (Mo-TAMs) intensively infiltrate diffuse
gliomas with remarkable heterogeneity. Using single-cell transcriptomics, we chart a …

Adrenomedullin (ADM) is a peptide hormone produced primarily in the adrenal glands,
playing a crucial role in various physiological processes. As well as improving vascular …

During the Renaissance period, recognition of the heart as the central organ of the
circulatory system propelled the understanding of the lymphatic system. Notably, Gaspare …

Calcitonin gene-related peptides alpha and beta (αCGRP, βCGRP), adrenomedullin (AM),
and adrenomedullin 2/intermedin (AM2/IMD) function in pain signaling, neuroimmune …

The lymphatic vascular system spans nearly every organ in the body and serves as an
important network that maintains fluid, metabolite, and immune cell homeostasis. Recently …

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly affecting premature
infants, with limited therapeutic options and increased long-term consequences …

Postural orthostatic tachycardia syndrome (POTS) is common in children, with an excessive
increment in heart rate when moving from the supine to upright position. It has significant …

Migraine and stroke are neurological disorders with significant global prevalence and
impact. Recent advances in migraine therapy have focused on the calcitonin gene-related …

The G protein–coupled receptor (GPCR) calcitonin receptor–like receptor (CLR) mediates
essential functions in several cell types and is implicated in cardiovascular pathologies, skin …

Lymphatic vessels conduct a diverse range of activities to sustain the integrity of surrounding
tissue. Besides facilitating the movement of lymph and its associated factors, lymphatic …