Mitochondria are the key energy-producing organelles and cellular source of reactive
species. They are responsible for managing cell life and death by a balanced homeostasis …

Mitochondrial function declines during ageing owing to the accumulation of deleterious
mitochondrial genomes and damage resulting from the localized generation of reactive …

Mitochondria are cellular energy powerhouses that play important roles in maintaining cell
survival, cell death and cellular metabolic homeostasis. Timely removal of damaged …

The last decade has been marked by tremendous progress in our understanding of the cell
biology of mitochondria, with the identification of molecules and mechanisms that regulate …

Erythropoiesis occurs mostly in bone marrow and ends in blood stream. Mature red blood
cells are generated from multipotent hematopoietic stem cells, through a complex maturation …

Mitochondria fuse and divide in response to cell demands and environment. Alterations in
mitochondrial dynamics underlie various human diseases, including cancer and neurologic …

Selective autophagy of mitochondria, known as mitophagy, is an important mitochondrial
quality control mechanism that eliminates damaged mitochondria. Mitophagy also mediates …

Autophagy not only recycles intracellular components to compensate for nutrient deprivation
but also selectively eliminates organelles to regulate their number and maintain quality …

Mitochondria are essential organelles that regulate cellular energy homeostasis and cell
death. The removal of damaged mitochondria through autophagy, a process called …

Mitochondria are primarily responsible for providing the contracting cardiac myocyte with a
continuous supply of ATP. However, mitochondria can rapidly change into death-promoting …