Gold nanoparticles and gold nanorods in the landscape of cancer therapy

P Kesharwani, R Ma, L Sang, M Fatima, A Sheikh… - Molecular cancer, 2023 - Springer
Cancer is a grievous disease whose treatment requires a more efficient, non-invasive
therapy, associated with minimal side effects. Gold nanoparticles possessing greatly …

[HTML][HTML] Therapeutic in vivo delivery of gene editing agents

A Raguram, S Banskota, DR Liu - Cell, 2022 - cell.com
In vivo gene editing therapies offer the potential to treat the root causes of many genetic
diseases. Realizing the promise of therapeutic in vivo gene editing requires the ability to …

A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles

TB Gandek, L van der Koog… - Advanced healthcare …, 2023 - Wiley Online Library
A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

J Yang, A Griffin, Z Qiang, J Ren - Signal transduction and targeted …, 2022 - nature.com
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

[HTML][HTML] A comprehensive review of toxicity of coal fly ash and its leachate in the ecosystem

Y Chen, Y Fan, Y Huang, X Liao, W Xu… - … and Environmental Safety, 2024 - Elsevier
Coal fly ash (CFA), a byproduct of coal combustion, is a hazardous industrial solid waste. Its
excessive global production, coupled with improper disposal practices, insufficient utilization …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies

AC Marques, PJ Costa, S Velho, MH Amaral - Journal of controlled release, 2020 - Elsevier
Standard cancer therapies sometimes fail to deliver chemotherapeutic drugs to tumor cells
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …