Microbes have remarkable capabilities to attach to the surface of implanted medical devices
and form biofilms that adversely impact device function and increase the risk of multidrug …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Thorough understanding of how to control cell behaviors including cell adhesion,
orientation, migration and differentiation on an artificial surface is critical in materials and life …

Cell-substrate interactions play a crucial role in the design of better biomaterials and
integration of implants with the tissues. Adhesion is the binding process of the cells to the …

The topographic features of an implant, which mechanically regulate cell behaviors and
functions, are critical for the clinical success in tissue regeneration. How cells sense and …

During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

This review reports the promising prospects of poly (lactic acid)(PLA) based nanostructured
materials considering two of their main potential uses, packaging and tissue engineering …

A key tenet of bone tissue engineering is the development of scaffold materials that can
stimulate stem cell differentiation in the absence of chemical treatment to become …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …