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Phytocannabinoids: origins and biosynthesis
T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders
S Singh, AS Grewal, R Grover, N Sharma, B Chopra… - Bioorganic …, 2022 - Elsevier
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
Current status and contemporary approaches to the discovery of antitumor agents from higher plants
G Agarwal, PJB Carcache, EM Addo… - Biotechnology advances, 2020 - Elsevier
Higher plant constituents have afforded clinically available anticancer drugs. These include
both chemically unmodified small molecules and their synthetic derivatives currently used or …
both chemically unmodified small molecules and their synthetic derivatives currently used or …
Emerging strategies for the activity assay and inhibitor screening of alpha-glucosidase
The high incidence of diabetes mellitus has caused widespread concern around the world,
and has quickly become one of the most prevalent and costly chronic diseases. Alpha …
and has quickly become one of the most prevalent and costly chronic diseases. Alpha …
Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus‐castus
Vitex agnus‐castus L.(Lamiaceae) is a medicinal plant historically used throughout the
Mediterranean region to treat menstrual cycle disorders, and is still used today as a clinically …
Mediterranean region to treat menstrual cycle disorders, and is still used today as a clinically …
Aldose reductase and protein tyrosine phosphatase 1B inhibitors as a promising therapeutic approach for diabetes mellitus
A Kousaxidis, A Petrou, V Lavrentaki… - European Journal of …, 2020 - Elsevier
Diabetes mellitus is a metabolic disease characterized by high blood glucose levels and
usually associated with several chronic pathologies. Aldose reductase and protein tyrosine …
usually associated with several chronic pathologies. Aldose reductase and protein tyrosine …
Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens
Worldwide, 463 million people are affected by diabetes of which the majority is diagnosed
with Type 2 Diabetes (T2D). T2D can ultimately lead to retinopathy, nephropathy, nerve …
with Type 2 Diabetes (T2D). T2D can ultimately lead to retinopathy, nephropathy, nerve …
Protein tyrosine phosphatase 1B inhibitors from natural sources
BT Zhao, DH Nguyen, DD Le, JS Choi, BS Min… - Archives of pharmacal …, 2018 - Springer
Since PTP1B enzyme was discovered in 1988, it has captured the research community's
attention. This landmark discovery has stimulated numerous research studies on a variety of …
attention. This landmark discovery has stimulated numerous research studies on a variety of …
Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic …
C Liang, L Kjaerulff, PR Hansen… - Journal of Natural …, 2021 - ACS Publications
Thirteen previously undescribed chromene meroterpenoids, capitachromenic acids A–M (3–
6, 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, and 11b), were identified from an ethyl acetate extract of …
6, 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, and 11b), were identified from an ethyl acetate extract of …
Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography–high-resolution …
In this paper, quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical
scavenging profiling combined with HPLC-HRMS-SPE-NMR were used for studying the …
scavenging profiling combined with HPLC-HRMS-SPE-NMR were used for studying the …