GJA1-20k and mitochondrial dynamics

D Shimura, RM Shaw - Frontiers in Physiology, 2022 - frontiersin.org
Connexin 43 (Cx43) is the primary gap junction protein of mammalian heart ventricles and is
encoded by the gene Gja1 which has a single coding exon and therefore cannot be spliced …

Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling

N Domingues, S Catarino, B Cristóvão… - The EMBO …, 2024 - embopress.org
A robust and efficient cellular response to lysosomal membrane damage prevents leakage
from the lysosome lumen into the cytoplasm. This response is understood to happen through …

[HTML][HTML] GJA1-20k, a Short Isoform of Connexin43, from Its Discovery to Its Potential Implication in Cancer Progression

S Fournier, J Clarhaut, L Cronier, A Monvoisin - Cells, 2025 - mdpi.com
The Connexin43 transmembrane protein (Cx43), encoded by the GJA1 gene, is a member
of a multigenic family of proteins that oligomerize to form hemichannels and intercellular …

Orally Delivered Milk-Derived Nanovesicles Loaded with Connexin 43 Peptides for Targeted Cardiac Ischemia-Reperfusion Therapy

SR Marsh, MR Amin, S Toldo, C Beard, AB Dogan… - bioRxiv, 2025 - biorxiv.org
Extracellular vesicles have emerged as promising nanocarriers for targeted drug delivery,
but their therapeutic potential is limited by challenges related to administration route …