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GJA1-20k and mitochondrial dynamics
Connexin 43 (Cx43) is the primary gap junction protein of mammalian heart ventricles and is
encoded by the gene Gja1 which has a single coding exon and therefore cannot be spliced …
encoded by the gene Gja1 which has a single coding exon and therefore cannot be spliced …
Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling
N Domingues, S Catarino, B Cristóvão… - The EMBO …, 2024 - embopress.org
A robust and efficient cellular response to lysosomal membrane damage prevents leakage
from the lysosome lumen into the cytoplasm. This response is understood to happen through …
from the lysosome lumen into the cytoplasm. This response is understood to happen through …
[HTML][HTML] GJA1-20k, a Short Isoform of Connexin43, from Its Discovery to Its Potential Implication in Cancer Progression
S Fournier, J Clarhaut, L Cronier, A Monvoisin - Cells, 2025 - mdpi.com
The Connexin43 transmembrane protein (Cx43), encoded by the GJA1 gene, is a member
of a multigenic family of proteins that oligomerize to form hemichannels and intercellular …
of a multigenic family of proteins that oligomerize to form hemichannels and intercellular …
Orally Delivered Milk-Derived Nanovesicles Loaded with Connexin 43 Peptides for Targeted Cardiac Ischemia-Reperfusion Therapy
Extracellular vesicles have emerged as promising nanocarriers for targeted drug delivery,
but their therapeutic potential is limited by challenges related to administration route …
but their therapeutic potential is limited by challenges related to administration route …