Recent advances in droplet microfluidics for single-cell analysis

Z Jiang, H Shi, X Tang, J Qin - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Single-cell manipulation and analysis is essential for studying many fundamental biological
processes and discovering cellular heterogeneity. Multi-parameter studies of intercellular …

Emerging droplet microfluidics

L Shang, Y Cheng, Y Zhao - Chemical reviews, 2017 - ACS Publications
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

N Shembekar, C Chaipan, R Utharala, CA Merten - Lab on a Chip, 2016 - pubs.rsc.org
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to
thousands of samples per second) and enables researchers to work with very limited …

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications

D Mark, S Haeberle, G Roth, F Von Stetten… - Microfluidics based …, 2010 - Springer
This review summarizes recent developments in microfluidic platform approaches. In
contrast to isolated application-specific solutions, a microfluidic platform provides a set of …

Droplet microfluidics—A tool for single‐cell analysis

HN Joensson… - Angewandte Chemie …, 2012 - Wiley Online Library
Droplet microfluidics allows the isolation of single cells and reagents in monodisperse
picoliter liquid capsules and manipulations at a throughput of thousands of droplets per …

Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

AB Theberge, F Courtois, Y Schaerli… - Angewandte Chemie …, 2010 - Wiley Online Library
Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …

Droplet microfluidics

SY Teh, R Lin, LH Hung, AP Lee - Lab on a Chip, 2008 - pubs.rsc.org
Droplet-based microfluidic systems have been shown to be compatible with many chemical
and biological reagents and capable of performing a variety of “digital fluidic” operations that …

Analytical detection techniques for droplet microfluidics—A review

Y Zhu, Q Fang - Analytica chimica acta, 2013 - Elsevier
In the last decade, droplet-based microfluidics has undergone rapid progress in the fields of
single-cell analysis, digital PCR, protein crystallization and high throughput screening. It has …

Two-phase microfluidic flows

CX Zhao, APJ Middelberg - Chemical Engineering Science, 2011 - Elsevier
Two phase systems are ubiquitous in processes and products, and in both cases
performance is maximized when precise control over the individual phases, and the …

[HTML][HTML] Förster resonance energy transfer–A spectroscopic nanoruler: Principle and applications

H Sahoo - Journal of Photochemistry and Photobiology C …, 2011 - Elsevier
Förster resonance energy transfer (FRET) in association with the recent advancements in
optical techniques provides a way to understand the detailed mechanisms in different …