Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
The recent progress in animal models of depression
Q Wang, MA Timberlake II, K Prall, Y Dwivedi - Progress in Neuro …, 2017 - Elsevier
Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …
and mortality. Despite the growing number of studies that have emerged, the precise …
Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review
The early-life social environment can induce stable changes that influence
neurodevelopment and mental health. Research focused on early-life adversity revealed …
neurodevelopment and mental health. Research focused on early-life adversity revealed …
Epigenetic inheritance: concepts, mechanisms and perspectives
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …
conditions, including psychopathologies, and their effects may even endure for several …
The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome
Stressful experiences during early-life can modulate the genetic programming of specific
brain circuits underlying emotional and cognitive aspects of behavioral adaptation to …
brain circuits underlying emotional and cognitive aspects of behavioral adaptation to …
Early-life experience, epigenetics, and the develo** brain
M Kundakovic, FA Champagne - Neuropsychopharmacology, 2015 - nature.com
Abstract Development is a dynamic process that involves interplay between genes and the
environment. In mammals, the quality of the postnatal environment is shaped by parent …
environment. In mammals, the quality of the postnatal environment is shaped by parent …
An overview of maternal separation effects on behavioural outcomes in mice: evidence from a four-stage methodological systematic review
SG Tractenberg, ML Levandowski… - Neuroscience & …, 2016 - Elsevier
Early life stress (ELS) developmental effects have been widely studied by preclinical
researchers. Despite the growing body of evidence from ELS models, such as the maternal …
researchers. Despite the growing body of evidence from ELS models, such as the maternal …
Effects of early-life stress on the brain and behaviors: implications of early maternal separation in rodents
M Nishi - International journal of molecular sciences, 2020 - mdpi.com
Early-life stress during the prenatal and postnatal periods affects the formation of neural
networks that influence brain function throughout life. Previous studies have indicated that …
networks that influence brain function throughout life. Previous studies have indicated that …
The role of DNA methylation in stress-related psychiatric disorders
Epigenetic modifications in response to traumatic experience and stress are emerging as
important factors in the long-term biological trajectories leading to stress-related psychiatric …
important factors in the long-term biological trajectories leading to stress-related psychiatric …
Age, introduction of solid feed and weaning are more important determinants of gut bacterial succession in piglets than breed and nursing mother as revealed by a …
G Bian, S Ma, Z Zhu, Y Su, EG Zoetendal… - Environmental …, 2016 - Wiley Online Library
A reciprocal cross‐fostering model with an obese typical Chinese piglet breed and a lean
Western breed was used to identify genetic and maternal effects on the acquisition and …
Western breed was used to identify genetic and maternal effects on the acquisition and …