Simple Summary Drugs are used to treat cancer. Most drugs available in the market are
chemosynthetic drugs and have side effects on the patient during and after the treatment, in …

In vitro human cell line models have been widely used for cancer pharmacogenomic studies
to predict clinical response, to help generate pharmacogenomic hypothesis for further …

Docetaxel (Taxotere®) has been one of the most important chemotherapeutic drugs for
cancer treatment since 1996. Although a large number of clinical studies have been …

Background Accumulating evidence confirm that aberrant microRNAs (miRNAs) expression
contributes to hepatocellular carcinoma (HCC) development and progression. Previous …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

Genomic research is one of the tools for elucidating the pathogenesis of diseases of global
health relevance and paving the research dimension to clinical and public health translation …

Mediation analysis is difficult when the number of potential mediators is larger than the
sample size. In this paper we propose new inference procedures for the indirect effect in the …

Abstract Purpose: Discovery of SNPs that predict a patient's risk of docetaxel-induced
neuropathy would enable treatment individualization to maximize efficacy and avoid …

Identification of the associations between microRNA molecules and human diseases from
large-scale heterogeneous biological data is an important step for understanding the …