An update on the pathogenesis of cholesterol gallstone disea... : Current Opinion in
Gastroenterology An update on the pathogenesis of cholesterol gallstone disease : Current …

The gallbladder stores and concentrates bile between meals. Gallbladder motor function is
regulated by bile acids via the membrane bile acid receptor, TGR5, and by neurohormonal …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Gallstone disease is very common in the Western world with an estimated prevalence of
10% to 15% in white adults, leading to significant morbidity, mortality, and considerable …

Gallstones are one of the most common digestive diseases with an estimated prevalence of
10%‐15% in adults living in the western world, where cholesterol‐enriched gallstones …

Phase separation of cholesterol crystals from supersaturated bile is still considered the key
event in cholesterol gallstone formation. In this review, we will first provide a basal …

Gallstone disease (GSD) is one of the most common biliary tract diseases worldwide in
which both genetic and environmental factors have roles in its pathogenesis. Biliary …

Biliary lithiasis is a common condition that leads to a significant health care burden
nationwide, with an estimated 20 million Americans (10%–15% of the adult population) …

Cholestatic liver diseases are named primarily due to the blockage of bile flow and buildup
of bile acids in the liver. Cholestasis can occur in cholangiopathies, fatty liver diseases, and …

The biliary tract collects, stores, concentrates, and delivers bile secreted by the liver. Its
motility is controlled by neurohormonal mechanisms with the vagus and splanchnic nerves …