The stiffness of living tissues and its implications for tissue engineering

CF Guimarães, L Gasperini, AP Marques… - Nature Reviews …, 2020 - nature.com
The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Rho GTPase signaling in cancer progression and dissemination

E Crosas-Molist, R Samain… - Physiological …, 2022 - journals.physiology.org
Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Apoptotic bodies: particular extracellular vesicles involved in intercellular communication

M Battistelli, E Falcieri - Advances in Medical Biochemistry …, 2021 - api.taylorfrancis.com
18.1. 1 Extracellular Vesicles The direct contact between two or more cells and the
interaction between the ligand and the receptor have been considered, for a long time, the …

Apoptosis and apoptotic body: disease message and therapeutic target potentials

X Xu, Y Lai, ZC Hua - Bioscience reports, 2019 - portlandpress.com
Apoptosis is widely known as programmed cell death eliciting no inflammatory responses.
The intricacy of apoptosis has been a focus of an array of researches, accumulating a wealth …

Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials

L Yu, G Zhu, Z Zhang, Y Yu, L Zeng, Z Xu… - Journal of …, 2023 - Springer
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …

[HTML][HTML] The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Actin dynamics in cell migration

M Schaks, G Giannone, K Rottner - Essays in biochemistry, 2019 - portlandpress.com
Cell migration is an essential process, both in unicellular organisms such as amoeba and as
individual or collective motility in highly developed multicellular organisms like mammals. It …

Apoptotic bodies: mechanism of formation, isolation and functional relevance

JP Santavanond, SF Rutter, GK Atkin-Smith… - New Frontiers …, 2021 - Springer
In the final stages of apoptosis, apoptotic cells can generate a variety of membrane-bound
vesicles known as apoptotic extracellular vesicles (ApoEVs). Apoptotic bodies (ApoBDs), a …

Blebology: principles of bleb-based migration

JM García-Arcos, A Jha, CM Waterman, M Piel - Trends in Cell Biology, 2024 - cell.com
Bleb-based migration, a conserved cell motility mode, has a crucial role in both
physiological and pathological processes. Unlike the well-elucidated mechanisms of …

[HTML][HTML] Cell membranes resist flow

Z Shi, ZT Graber, T Baumgart, HA Stone, AE Cohen - Cell, 2018 - cell.com
The fluid-mosaic model posits a liquid-like plasma membrane, which can flow in response to
tension gradients. It is widely assumed that membrane flow transmits local changes in …