[HTML][HTML] Fixing the GAP: The role of RhoGAPs in cancer

G Kreider-Letterman, NM Carr… - European journal of cell …, 2022 - Elsevier
Cancer progression and metastasis are processes that involve significant cellular changes.
Many of these changes include alterations in the activity of the Rho GTPase family of …

Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster

A Frappaolo, R Piergentili, MG Giansanti - Cells, 2022 - mdpi.com
Drosophila dividing spermatocytes offer a highly suitable cell system in which to investigate
the coordinated reorganization of microtubule and actin cytoskeleton systems during cell …

[HTML][HTML] Urban dust particles disrupt mitotic progression by dysregulating Aurora kinase B-related functions

J Ryu, SH Lee, S Kim, JW Jeong, KS Kim… - Journal of Hazardous …, 2023 - Elsevier
Particulate matter (PM), a major component of outdoor air pollution, damages DNA and
increases the risk of cancer. Although the harmful effects of PM at the genomic level are …

The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization

U Batman, J Deretic, EN Firat-Karalar - PLoS Biology, 2022 - journals.plos.org
Precise spatiotemporal control of microtubule nucleation and organization is critical for
faithful segregation of cytoplasmic and genetic material during cell division and signaling via …

[HTML][HTML] Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes

A Bakshi, FE Iturra, A Alamban, M Rosas-Salvans… - Cell, 2023 - cell.com
Cytoplasmic divisions are thought to rely on nuclear divisions and mitotic signals. We
demonstrate in Drosophila embryos that cytoplasm can divide repeatedly without nuclei and …

Going with the flow: insights from Caenorhabditis elegans zygote polarization

AG Gubieda, JR Packer, I Squires… - … of the Royal …, 2020 - royalsocietypublishing.org
Cell polarity is the asymmetric distribution of cellular components along a defined axis.
Polarity relies on complex signalling networks between conserved patterning proteins …

Cleavage furrow positioning in dividing Dictyostelium cells

A Okada, S Yumura - Cytoskeleton, 2023 - Wiley Online Library
Accurate placement of the cleavage furrow is crucial for successful cell division. Recent
advancements have revealed that diverse mechanisms have evolved across different …

A gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency

C Lagresle-Peyrou, A Olichon, H Sadek… - …, 2020 - pmc.ncbi.nlm.nih.gov
Svere combined immunodeficiencies (SCID) constitute a heterogeneous group of life-
threatening genetic disorders that typically present in the first year of life. They are defined …

Comparative analysis of the roles of non-muscle myosin-IIs in cytokinesis in budding yeast, fission yeast, and mammalian cells

K Wang, H Okada, E Bi - Frontiers in cell and developmental biology, 2020 - frontiersin.org
The contractile ring, which plays critical roles in cytokinesis in fungal and animal cells, has
fascinated biologists for decades. However, the basic question of how the non-muscle …

Non-muscle myosin II drives critical steps of nematocyst morphogenesis

N Garg, UK Štibler, B Eismann, M Mercker… - Iscience, 2023 - cell.com
Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …