[HTML][HTML] Fixing the GAP: The role of RhoGAPs in cancer
G Kreider-Letterman, NM Carr… - European journal of cell …, 2022 - Elsevier
Cancer progression and metastasis are processes that involve significant cellular changes.
Many of these changes include alterations in the activity of the Rho GTPase family of …
Many of these changes include alterations in the activity of the Rho GTPase family of …
Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster
Drosophila dividing spermatocytes offer a highly suitable cell system in which to investigate
the coordinated reorganization of microtubule and actin cytoskeleton systems during cell …
the coordinated reorganization of microtubule and actin cytoskeleton systems during cell …
[HTML][HTML] Urban dust particles disrupt mitotic progression by dysregulating Aurora kinase B-related functions
J Ryu, SH Lee, S Kim, JW Jeong, KS Kim… - Journal of Hazardous …, 2023 - Elsevier
Particulate matter (PM), a major component of outdoor air pollution, damages DNA and
increases the risk of cancer. Although the harmful effects of PM at the genomic level are …
increases the risk of cancer. Although the harmful effects of PM at the genomic level are …
The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization
Precise spatiotemporal control of microtubule nucleation and organization is critical for
faithful segregation of cytoplasmic and genetic material during cell division and signaling via …
faithful segregation of cytoplasmic and genetic material during cell division and signaling via …
[HTML][HTML] Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes
Cytoplasmic divisions are thought to rely on nuclear divisions and mitotic signals. We
demonstrate in Drosophila embryos that cytoplasm can divide repeatedly without nuclei and …
demonstrate in Drosophila embryos that cytoplasm can divide repeatedly without nuclei and …
Going with the flow: insights from Caenorhabditis elegans zygote polarization
AG Gubieda, JR Packer, I Squires… - … of the Royal …, 2020 - royalsocietypublishing.org
Cell polarity is the asymmetric distribution of cellular components along a defined axis.
Polarity relies on complex signalling networks between conserved patterning proteins …
Polarity relies on complex signalling networks between conserved patterning proteins …
Cleavage furrow positioning in dividing Dictyostelium cells
A Okada, S Yumura - Cytoskeleton, 2023 - Wiley Online Library
Accurate placement of the cleavage furrow is crucial for successful cell division. Recent
advancements have revealed that diverse mechanisms have evolved across different …
advancements have revealed that diverse mechanisms have evolved across different …
A gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency
C Lagresle-Peyrou, A Olichon, H Sadek… - …, 2020 - pmc.ncbi.nlm.nih.gov
Svere combined immunodeficiencies (SCID) constitute a heterogeneous group of life-
threatening genetic disorders that typically present in the first year of life. They are defined …
threatening genetic disorders that typically present in the first year of life. They are defined …
Comparative analysis of the roles of non-muscle myosin-IIs in cytokinesis in budding yeast, fission yeast, and mammalian cells
The contractile ring, which plays critical roles in cytokinesis in fungal and animal cells, has
fascinated biologists for decades. However, the basic question of how the non-muscle …
fascinated biologists for decades. However, the basic question of how the non-muscle …
Non-muscle myosin II drives critical steps of nematocyst morphogenesis
N Garg, UK Štibler, B Eismann, M Mercker… - Iscience, 2023 - cell.com
Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …