Neurobiology and systems biology of stress resilience

R Kalisch, SJ Russo, MB Müller - Physiological reviews, 2024 - journals.physiology.org
Stress resilience is the phenomenon that some people maintain their mental health despite
exposure to adversity or show only temporary impairments followed by quick recovery …

[HTML][HTML] A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration

L Oblak, J van der Zaag, AT Higgins-Chen… - Ageing research …, 2021 - Elsevier
Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

DNA methylation-based predictors of health: applications and statistical considerations

PD Yousefi, M Suderman, R Langdon… - Nature Reviews …, 2022 - nature.com
DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

[LIVRE][B] Multisystemic resilience: Adaptation and transformation in contexts of change

M Ungar - 2021 - books.google.com
" Across diverse disciplines, the term resilience is appearing more and more often. However,
while each discipline has developed theory and models to explain the resilience of the …

The resilience framework as a strategy to combat stress-related disorders

R Kalisch, DG Baker, U Basten, MP Boks… - Nature human …, 2017 - nature.com
Consistent failure over the past few decades to reduce the high prevalence of stress-related
disorders has motivated a search for alternative research strategies. Resilience refers to the …

Deconstructing and reconstructing resilience: A dynamic network approach

R Kalisch, AOJ Cramer, H Binder… - Perspectives on …, 2019 - journals.sagepub.com
Resilience is still often viewed as a unitary personality construct that, as a kind of
antinosological entity, protects individuals against stress-related mental problems. However …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
The process of aging results in a host of changes at the cellular and molecular levels, which
include senescence, telomere shortening, and changes in gene expression. Epigenetic …

A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches

SH Parade, L Huffhines, TE Daniels, LR Stroud… - Translational …, 2021 - nature.com
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

HIV-1 infection accelerates age according to the epigenetic clock

S Horvath, AJ Levine - The Journal of infectious diseases, 2015 - academic.oup.com
Background. Infection with human immunodeficiency virus type 1 (HIV) is associated with
clinical symptoms of accelerated aging, as evidenced by the increased incidence and …

Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood

NP Daskalakis, A Iatrou, C Chatzinakos, A Jajoo… - Science, 2024 - science.org
The molecular pathology of stress-related disorders remains elusive. Our brain multiregion,
multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder …