Current advances in photodynamic therapy (PDT) and the future potential of PDT-combinatorial cancer therapies

N Alvarez, A Sevilla - International Journal of Molecular Sciences, 2024 - mdpi.com
Photodynamic therapy (PDT) is a two-stage treatment that implies the use of light energy,
oxygen, and light-activated compounds (photosensitizers) to elicit cancerous and …

Crucial Breakthrough of BODIPY‐Based NIR‐II Fluorescent Emitters for Advanced Biomedical Theranostics

X Hu, Z Fang, C Zhu, Y Yang, Z Yang… - Advanced Functional …, 2024 - Wiley Online Library
Fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–1700 nm) has
aroused immense attention for biomedical applications, offering exceptional advantages …

NIR‐II photoacoustic imaging‐guided oxygen delivery and controlled release improves photodynamic therapy for hepatocellular carcinoma

S Zeng, J Chen, R Gao, R Chen, Q Xue… - Advanced …, 2024 - Wiley Online Library
Hypoxia, a prominent hallmark of hepatocellular carcinoma (HCC), undermines curative
outcomes, elevates recurrence rates, and fosters metastasis, particularly during …

“Three birds with one stone” nanoplatform: Efficient near‐infrared‐triggered type‑I AIE photosensitizer for mitochondria‐targeted photodynamic therapy against …

S Liu, Y Pei, Y Sun, Z Wang, H Chen, D Zhu… - …, 2024 - Wiley Online Library
Currently three major problems seriously limit the practical application of cancer
photodynamic therapy (PDT):(i) the hypoxic tumor microenvironment (TME);(ii) low …

Samarium doped carbon dots for near-infrared photo-therapy

H Shi, Y Yin, H Xu, X Qu, H Wang, Z An - Chemical Engineering Journal, 2024 - Elsevier
Photo-assisted tumor therapy, encompassing photodynamic therapy (PDT) and
photothermal therapy (PTT), has garnered considerable attention as a promising approach …

Deciphering Oxygen‐Independent Augmented Photodynamic Oncotherapy by Facilitating the Separation of Electron‐Hole Pairs

X Hu, Z Fang, F Sun, C Zhu, M Jia, X Miao… - Angewandte …, 2024 - Wiley Online Library
Develo** Type‐I photosensitizers provides an attractive approach to solve the dilemma of
inadequate efficacy of photodynamic therapy (PDT) caused by the inherent oxygen …

Bithiophene‐Functionalized Infrared Two‐Photon Absorption Metal Complexes as Single‐Molecule Platforms for Synergistic Photodynamic, Photothermal, and …

XL Li, MF Wang, LZ Zeng, GK Li… - Angewandte Chemie …, 2024 - Wiley Online Library
A planar conjugated ligand functionalized with bithiophene and its Ru (II), Os (II), and Ir (III)
complexes have been constructed as single‐molecule platform for synergistic …

[HTML][HTML] Natural-product-based, carrier-free, noncovalent nanoparticles for tumor chemo-photodynamic combination therapy

Z Wang, L Yang - Pharmacological Research, 2024 - Elsevier
Cancer, with its diversity, heterogeneity, and complexity, is a significant contributor to global
morbidity, disability, and mortality, highlighting the necessity for transformative treatment …

Dual‐functional injectable hydrogel for osteoarthritis treatments

L Lei, R Cong, Y Ni, X Cui, X Wang… - Advanced …, 2024 - Wiley Online Library
Osteoarthritis (OA) is a prevalent, chronic degenerative disease that affects people
worldwide. It is characterized by the destruction of cartilage and inflammatory reactions …

Metal–organic framework nanocomposites in conquering hypoxia for tumor therapy

S Zhou, F Jia, Y Wei, J Du, J Liu… - Advanced Functional …, 2024 - Wiley Online Library
Hypoxia, as a distinctive feature of tumors, is closely related to tumor recurrence, metastasis,
and treatment resistance. Metal–organic framework (MOF) exhibits an increasing number of …