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Second harmonic generation microscopy: a powerful tool for bio-imaging
Second harmonic generation (SHG) microscopy is an important optical imaging technique in
a variety of applications. This article describes the history and physical principles of SHG …
a variety of applications. This article describes the history and physical principles of SHG …
Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
Current anti-VEGF therapies for colorectal cancer (CRC) provide limited survival benefit, as
tumors rapidly develop resistance to these agents. Here, we have uncovered an …
tumors rapidly develop resistance to these agents. Here, we have uncovered an …
Cancer-associated angiogenesis: the endothelial cell as a checkpoint for immunological patrolling
Simple Summary A clinical decision and study design investigating the level and extent of
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic …
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic …
Imaging cell biology in live animals: ready for prime time
Time-lapse fluorescence microscopy is one of the main tools used to image subcellular
structures in living cells. Yet for decades it has been applied primarily to in vitro model …
structures in living cells. Yet for decades it has been applied primarily to in vitro model …
Intravital microscopy: a practical guide on imaging intracellular structures in live animals
Intravital microscopy is an extremely powerful tool that enables imaging several biological
processes in live animals. Recently, the ability to image subcellular structures in several …
processes in live animals. Recently, the ability to image subcellular structures in several …
Quantitative blood flow estimation in vivo by optical speckle image velocimetry
<? TeX-2pc-22pc?> Speckle-based methods are popular non-invasive, label-free full-field
optical techniques for imaging blood flow maps at single vessel resolution with a high …
optical techniques for imaging blood flow maps at single vessel resolution with a high …
Designing a large field-of-view two-photon microscope using optical invariant analysis
Conventional two-photon microscopy (TPM) is capable of imaging neural dynamics with
subcellular resolution, but it is limited to a field-of-view (FOV) diameter< 1 mm. Although …
subcellular resolution, but it is limited to a field-of-view (FOV) diameter< 1 mm. Although …
Multiphoton intravital microscopy of rodents
Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …
dynamic interactions between these elements. To study the behaviour and fate of individual …
Recent advances in intravital microscopy for investigation of dynamic cellular behavior in vivo
Currently, most biological research relies on conventional experimental techniques that
allow only static analyses at certain time points in vitro or ex vivo. However, if one could …
allow only static analyses at certain time points in vitro or ex vivo. However, if one could …