The Subthalamic Nucleus (STh) is an oval-shaped diencephalic structure located ventrally
to the thalamus, playing a fundamental role in the circuitry of the basal ganglia. In addition to …

Objective To investigate whether functional sweet spots of deep brain stimulation (DBS) in
the subthalamic nucleus (STN) can predict motor improvement in Parkinson disease (PD) …

Several single-center studies and one large multicenter clinical trial demonstrated that
directional deep brain stimulation (DBS) could optimize the volume of tissue activated (VTA) …

Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Objective Subthalamic deep brain stimulation (DBS) is an established therapy for
Parkinson's disease. Connectomic DBS modeling is a burgeoning subfield of research …

Medical imaging has played a major role in defining the general anatomical targets for deep
brain stimulation (DBS) therapies. However, specifics on the underlying brain circuitry that is …

Objective Deep brain stimulation (DBS) requires accurate localization of the anatomical
target structure, and the precise placement of the DBS electrode within it. Ultra-high field 7 …

Background Unilateral subthalamic nucleus (STN) ablation using magnetic resonance–
guided focused ultrasound (MRgFUS) is being explored as a new treatment for asymmetric …

Deep brain stimulation of the subthalamic nucleus has become a standard therapy for
Parkinson's disease. Despite extensive experience, however, the precise target of optimal …

Background Subthalamic deep brain stimulation (DBS) is an effective surgical treatment for
Parkinson's disease and continues to advance technologically with an enormous parameter …