Acute-on-chronic liver failure: Far to go—A review

J Luo, J Li, P Li, X Liang, HM Hassan, R Moreau, J Li - Critical Care, 2023 - Springer
Acute-on-chronic liver failure (ACLF) has been recognized as a severe clinical syndrome
based on the acute deterioration of chronic liver disease and is characterized by organ …

Intensive care management of acute-on-chronic liver failure

G Perricone, T Artzner, E De Martin, R Jalan… - Intensive care …, 2023 - Springer
Acute-on-chronic liver failure (ACLF) is a clinical syndrome defined by an acute deterioration
of the liver function associated with extrahepatic organ failures requiring intensive care …

Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US

KR Patidar, JM Belcher, KR Regner, SAS Hillien… - Journal of …, 2023 - Elsevier
Background & Aims Acute kidney injury (AKI) in cirrhosis is common and associated with
high morbidity, but the incidence rates of different etiologies of AKI are not well described in …

Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

DS Kim, YI Yoon, BK Kim, A Choudhury… - Hepatology …, 2024 - Springer
Liver transplantation is a highly complex and challenging field of clinical practice. Although it
was originally developed in western countries, it has been further advanced in Asian …

Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure

RK Jagdish, A Roy, K Kumar, M Premkumar… - Frontiers in …, 2023 - frontiersin.org
Cirrhosis transcends various progressive stages from compensation to decompensation
driven by the severity of portal hypertension. The downstream effect of increasing portal …

Acute-on-chronic liver failure (ACLF) in 2022: have novel treatment paradigms already arrived?

N Abbas, N Rajoriya, AM Elsharkawy… - Expert review of …, 2022 - Taylor & Francis
Introduction Acute-on-chronic failure (ACLF) is a recognized syndrome in patients with
chronic liver disease and is characterized by acute decompensation, organ failure (s), and a …

Acute-on-chronic liver failure: Controversies and consensus

NLY Ngu, E Flanagan, S Bell… - World journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Acute-on-chronic liver failure (ACLF) is a poorly defined syndrome characterised by rapid
clinical deterioration in patients with chronic liver disease. Consequences include high short …

Inflammation drives pathogenesis of early intestinal failure-associated liver disease

SC Fligor, ST Tsikis, TI Hirsch, A Jain, L Sun… - Scientific Reports, 2024 - nature.com
Patients with intestinal failure who receive long-term parenteral nutrition (PN) often develop
intestinal failure-associated liver disease (IFALD). Although there are identified risk factors …

Larsucosterol: endogenous epigenetic regulator for treating chronic and acute liver diseases

Y Wang, J Ren, S Ren - American Journal of Physiology …, 2024 - journals.physiology.org
Larsucosterol, a potent endogenous epigenetic regulator, has been reported to play a
significant role in lipid metabolism, inflammatory responses, and cell survival. The …

Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!

JS Bajaj, A Choudhury, V Kumaran, F Wong… - American Journal of …, 2024 - Elsevier
Decompensated cirrhosis and hepatocellular cancer are major risk factors for mortality
worldwide. Liver transplantation (LT), both live-donor LT or deceased-donor LT, are …