Cancer remains to be one of the leading causes of death in the United States and around
the world. The advent of modern drug-targeted therapies has undeniably improved cancer …

Protein tyrosine phosphatases (PTPs) are considered to be involved in the etiology of
diabetes mellitus, neural diseases such as Alzheimer's and Parkinson's disease, regulation …

Background: Endocrine-disrupting chemicals (EDCs) influence the activity of estrogen
receptors (ERs) and alter the function of the endocrine system. However, the diversity of …

Nontoxic naturally occurring compounds, especially those from dietary sources, are
receiving increasing consideration for prevention and treatment of diseases including …

Protein tyrosine phosphatases (PTPs) play a critical role in physiological signaling pathways
by controlling the level of tyrosine phosphorylation. The past decade has seen a vast …

Since Branemark's findings, titanium-based alloys have been widely used in implantology.
However, their success in dental implants is not known when considering the heterogenicity …

It is important to understand the cellular and molecular events that occur at the cell–material
interface of implants used for bone repair. The mechanisms involved in the initial stages of …

Cancer represents a set of more than 100 diseases, including malignant tumors from
different locations. Strategies inducing differentiation have had limited success in the …

The review is focused on the bacterial protein tyrosine phosphatases (PTPs) utilized by
bacteria as virulence factors necessary for pathogenicity. The inhibition of bacterial PTPs …

Background: Src kinase plays a critical role in bone metabolism, particularly in osteoclasts.
However, the ability of Src kinase to modulate the activity of other bone cells is less well …