CRISPR/Cas9 therapeutics: progress and prospects

T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - Signal transduction and …, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

[HTML][HTML] Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies

K Dhama, F Nainu, A Frediansyah, MI Yatoo… - Journal of infection and …, 2023 - Elsevier
Newly emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
are continuously posing high global public health concerns and panic resulting in waves of …

Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

Efficacy and safety of a recombinant plant-based adjuvanted Covid-19 vaccine

KJ Hager, G Pérez Marc, P Gobeil… - New England journal …, 2022 - Mass Medical Soc
Abstract Background Coronavirus-like particles (CoVLP) that are produced in plants and
display the prefusion spike glycoprotein of the original strain of severe acute respiratory …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Update on the effectiveness of COVID-19 vaccines on different variants of SARS-CoV-2

N Firouzabadi, P Ghasemiyeh, F Moradishooli… - International …, 2023 - Elsevier
It has been more than three years since the first emergence of coronavirus disease 2019
(COVID-19) and millions of lives have been taken to date. Like most pandemics caused by …

Delta variant (B. 1.617. 2) of SARS-CoV-2: Mutations, impact, challenges and possible solutions

M Dhawan, A Sharma, N Priyanka… - Human vaccines & …, 2022 - Taylor & Francis
Since commencement of COVID-19 pandemic, several SARS-CoV-2 variants have emerged
amid containment efforts via vaccination. The Delta variant (B. 1.617. 2), discovered in …

In search of a pan-coronavirus vaccine: Next-generation vaccine design and immune mechanisms

S Cankat, MU Demael, L Swadling - Cellular & molecular immunology, 2024 - nature.com
Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …

Association between vaccination and acute myocardial infarction and ischemic stroke after COVID-19 infection

YE Kim, K Huh, YJ Park, KR Peck, J Jung - Jama, 2022 - jamanetwork.com
Methods| We conducted a retrospective cohort study to compare the incidence of AMI and
ischemic stroke after COVID-19 infection between patients who were never vaccinated and …

Household secondary attack rates of SARS-CoV-2 by variant and vaccination status: an updated systematic review and meta-analysis

ZJ Madewell, Y Yang, IM Longini… - JAMA network …, 2022 - jamanetwork.com
Importance An overall household secondary attack rate (SAR) of 18.9%(95% CI, 16.2%-
22.0%) through June 17, 2021 was previously reported for SARS-CoV-2. Emerging variants …