Individualizing patient treatment is a core objective of the medical field. Reaching this
objective has been elusive owing to the complex set of factors contributing to both disease …

Leigh syndrome is a rare, complex, and incurable early onset (typically infant or early
childhood) mitochondrial disorder with both phenotypic and genetic heterogeneity. The …

Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …

Mitochondrial diseases are a heterogeneous group of rare genetic disorders that can be
caused by mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA). Mutations in mtDNA …

Rare diseases are heterogeneous life-threatening or seriously debilitating conditions that
affect< 1 in 2000 individuals, and most have a genetic component. The diagnostic process is …

ÖZ Üremeye Yardımcı Tedavi Yöntemleri (ÜYTY) çocuk sahibi olmak isteyen çiftler için tüm
Dünyada yaygın olarak kullanılmaktadır. Hatta çoğu ülkede tüp bebek ile ilgili etik tartışmalar …

The mitochondrial genome of a species is an essential resource for its effective conservation
and phylogenetic studies. In this article, we present sequencing and characterization of the …

Biomarkers are a key tool in medicine, especially in the domain of personalized medicine.
They are valuable for the early detection, prognosis, and diagnosis of disease as well as for …

The revolutionary foundation for eradicating the burden of severe mitochondrial DNA
(mtDNA) disease transmission was laid in 2017 with the first-ever in-vitro mitochondrial …

Genetik araştırma ve uygulamalar, mitokondriyal gen defektlerinin sebep olduğu
mitokondriyal hastalıklar için alternatif bir yöntem sunmaktadır. Günümüzde mitokondriyal …