Members of the plant family Leguminosae (Fabaceae) are unique in that they have evolved
a symbiotic relationship with rhizobia (a group of soil bacteria that can fix atmospheric …

Fumaric, l‐malic and citric acids are intermediates of the oxidative tricarboxylic acid (TCA)
cycle which in eukaryotes is localized in mitochondria. These organic acids are synthesized …

Nitrogen fixation within legume nodules results from a complex metabolic exchange
between bacteria of the family Rhizobiaciae and the plant host. Carbon is supplied to the …

Biological nitrogen fixation is vital to nutrient cycling in the biosphere and is the major route
by which atmospheric dinitrogen (N 2) is reduced to ammonia. The largest single …

We report an inborn error of the tricarboxylic acid cycle, fumarase deficiency, in two siblings
born to first cousin parents. They presented with progressive encephalopathy, dystonia …

One of the paradigms of symbiotic nitrogen fixation has been that bacteroids reduce N 2 to
ammonium and secrete it without assimilation into amino acids. This has recently been …

Rhizobia are a diverse group of Gram-negative bacteria comprised of the genera
Rhizobium, Bradyrhizobium, Mesorhizobium, Sinorhizobium and Azorhizobium. A unifying …

The Irr protein from the bacterium Bradyrhizobium japonicum is expressed under iron
limitation to mediate iron control of haem biosynthesis. The regulatory input to Irr is the status …

Rhizobia are soil bacteria able to establish symbiosis with diverse host plants. Specifically,
Sinorhizobium fredii is a soil bacterium that forms nitrogen-fixing root nodules in diverse …

Perception and response to nutritional iron availability by bacteria are essential to control
cellular iron homeostasis. The Irr protein from Bradyrhizobium japonicum senses iron …