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Polymer folding through active processes recreates features of genome organization
From proteins to chromosomes, polymers fold into specific conformations that control their
biological function. Polymer folding has long been studied with equilibrium thermodynamics …
biological function. Polymer folding has long been studied with equilibrium thermodynamics …
Chromosome dynamics during interphase: a biophysical perspective
The dynamic nature of chromosome organization plays a central role in the regulation of
many crucial processes, such as DNA transcription and replication. However, the molecular …
many crucial processes, such as DNA transcription and replication. However, the molecular …
Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation
In most bacteria, chromosome segregation is driven by the ParAB S system where the
CTPase protein ParB loads at the parS site to trigger the formation of a large partition …
CTPase protein ParB loads at the parS site to trigger the formation of a large partition …
Activity-induced collapse and arrest of active polymer rings
We investigate, using numerical simulations, the conformations of isolated active ring
polymers. We find that their behavior depends crucially on their size: Short rings (N≲ 100) …
polymers. We find that their behavior depends crucially on their size: Short rings (N≲ 100) …
Temporally correlated active forces drive segregation and enhanced dynamics in chromosome polymers
Understanding the mechanisms governing the structure and dynamics of flexible polymers
like chromosomes, especially the signatures of motor-driven active processes, is of great …
like chromosomes, especially the signatures of motor-driven active processes, is of great …
Tangentially driven active polar linear polymers—An analytical study
The conformational and dynamical properties of isolated flexible active polar linear polymers
(APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear …
(APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear …
Conformation and dynamics of partially active linear polymers
We perform numerical simulations of isolated, partially active polymers, driven out-of-
equilibrium by a fraction of their monomers. We show that, if the active beads are all …
equilibrium by a fraction of their monomers. We show that, if the active beads are all …
Migration and separation of polymers in nonuniform active baths
Polymerlike structures are ubiquitous in nature and synthetic materials. Their configurational
and migration properties are often affected by crowded environments leading to nonthermal …
and migration properties are often affected by crowded environments leading to nonthermal …
Self-organized states from solutions of active ring polymers in bulk and under confinement
In the present work, we study, by means of numerical simulations, the structural and
dynamical behavior of a suspension of active ring polymers in bulk and under lateral …
dynamical behavior of a suspension of active ring polymers in bulk and under lateral …
Conformation and dynamics of a self-avoiding active flexible polymer
We investigate conformations and dynamics of a polymer considering its monomers to be
active Brownian particles. This active polymer shows very intriguing physical behavior which …
active Brownian particles. This active polymer shows very intriguing physical behavior which …