φ29 family of phages

WJJ Meijer, JA Horcajadas, M Salas - Microbiology and molecular …, 2001 - Am Soc Microbiol
Continuous research spanning more than three decades has made the Bacillus
bacteriophage φ29 a paradigm for several molecular mechanisms of general biological …

Promoter clearance and escape in prokaryotes

LM Hsu - Biochimica et Biophysica Acta (BBA)-Gene Structure …, 2002 - Elsevier
Promoter escape is the last stage of transcription initiation when RNA polymerase, having
initiated de novo phosphodiester bond synthesis, must begin to relinquish its hold on …

Identification of the CRP regulon using in vitro and in vivo transcriptional profiling

D Zheng, C Constantinidou, JL Hobman… - Nucleic acids …, 2004 - academic.oup.com
The Escherichia coli cyclic AMP receptor protein (CRP) is a global regulator that controls
transcription initiation from more than 100 promoters by binding to a specific DNA sequence …

Mechanism of regulation of transcription initiation by ppGpp. I. Effects of ppGpp on transcription initiation in vivo and in vitro

MM Barker, T Gaal, CA Josaitis, RL Gourse - Journal of molecular biology, 2001 - Elsevier
To determine the role of ppGpp in both negative and positive regulation of transcription
initiation during exponential growth in Escherichia coli, we examined transcription in …

Identification of an UP element consensus sequence for bacterial promoters

ST Estrem, T Gaal, W Ross… - Proceedings of the …, 1998 - National Acad Sciences
The UP element, a component of bacterial promoters located upstream of the− 35 hexamer,
increases transcription by interacting with the RNA polymerase α-subunit. By using a …

The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting

NB Reppas, JT Wade, GM Church, K Struhl - Molecular cell, 2006 - cell.com
We perform a genome-wide analysis of the transition between transcriptional initiation and
elongation in Escherichia coli by determining the association of core RNA polymerase …

Plasmid copy-number control and better-than-random segregation genes of pSM19035 share a common regulator

AB De la Hoz, S Ayora, I Sitkiewicz… - Proceedings of the …, 2000 - National Acad Sciences
Transcription initiation of the copy-number control and better-than-random segregation
genes of the broad-host-range and low-copy-number plasmid pSM19035 are subjected to …

A regulatory protein that interferes with activator-stimulated transcription in bacteria

S Nakano, MM Nakano, Y Zhang… - Proceedings of the …, 2003 - National Acad Sciences
Transcriptional activator proteins in bacteria often operate by interaction with the C-terminal
domain of the α-subunit of RNA polymerase (RNAP). Here we report the discovery of an …

Protein–protein contacts that activate and repress prokaryotic transcription

A Hochschild, SL Dove - Cell, 1998 - cell.com
Protein–Protein Contacts Minireview that Activate and Repress Prokaryotic Transcription
with either the subunit (its C-terminal domain [CTD], in particular) or the 70 subunit (the most …

Repression of transcription initiation in bacteria

F Rojo - Journal of bacteriology, 1999 - Am Soc Microbiol
Bacteria live in habitats of frequently changing conditions and have evolved very
sophisticated responses to adapt to environmental changes. These responses most …