Plasmodium sporozoite transmission is a critical population bottleneck in parasite life-cycle
progression and, hence, a target for prophylactic drugs and vaccines. The recent progress of …

P lasmodium spp. and T oxoplasma gondii are important human and veterinary pathogens.
These parasites possess an unusual double membrane structure located directly below the …

Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …

Stage-specific transcription is a fundamental biological process in the life cycle of the
Plasmodium parasite. Proteins containing the AP2 DNA-binding domain are responsible for …

Plasmodium falciparum and Plasmodium vivax cause the majority of human malaria cases.
Research efforts predominantly focus on P. falciparum because of the clinical severity of …

Cell division across members of the protozoan parasite phylum Apicomplexa displays a
surprising diversity between different species as well as between different life stages of the …

Malaria parasites undergo a complex life cycle between their hosts and vectors. During this
cycle the parasites invade different types of cells, migrate across barriers, and transfer from …

Over the past decade, major advances in imaging techniques have enhanced our
understanding of Plasmodium spp. parasites and their interplay with mammalian hosts and …

Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter
host cells. Here we show that the actin filament-binding protein coronin regulates gliding …

Leishmania parasites must survive and proliferate in two vastly different environments–the
guts of poikilothermic sandflies and the antigen-presenting cells of homeothermic mammals …