[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

Evolution of the SARS‐CoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission

LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

B Meng, A Abdullahi, IATM Ferreira, N Goonawardane… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …

An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

LA VanBlargan, JM Errico, PJ Halfmann, SJ Zost… - Nature medicine, 2022 - nature.com
The emergence of the highly transmissible B. 1.1. 529 Omicron variant of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody …

Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …

Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants

EK Accorsi, A Britton, KE Fleming-Dutra, ZR Smith… - Jama, 2022 - jamanetwork.com
Importance Assessing COVID-19 vaccine performance against the rapidly spreading SARS-
CoV-2 Omicron variant is critical to inform public health guidance. Objective To estimate the …

Population immunity and Covid-19 severity with Omicron variant in South Africa

SA Madhi, G Kwatra, JE Myers, W Jassat… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The B. 1.1. 529 (omicron) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first identified on November 25, 2021, in Gauteng …

[HTML][HTML] Virological characteristics of the SARS-CoV-2 Omicron BA. 2 spike

D Yamasoba, I Kimura, H Nasser, Y Morioka, N Nao… - Cell, 2022 - cell.com
Soon after the emergence and global spread of the SARS-CoV-2 Omicron lineage BA. 1,
another Omicron lineage, BA. 2, began outcompeting BA. 1. The results of statistical analysis …

Estimated effectiveness of COVID-19 vaccines against Omicron or Delta symptomatic infection and severe outcomes

SA Buchan, H Chung, KA Brown, PC Austin… - JAMA network …, 2022 - jamanetwork.com
Importance The incidence of SARS-CoV-2 infection, including among individuals who have
received 2 doses of COVID-19 vaccine, increased substantially following the emergence of …