Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS
spectra from screening small molecules in fields such as environmental analysis, drug …

The ability to switch between different lifestyles allows bacterial pathogens to thrive in
diverse ecological niches,. However, a molecular understanding of their lifestyle changes …

INTRODUCTION A complete view of human biology can only be achieved by studying the
molecular components of its smallest functional unit, the cell. Cells are internally organized …

Ubiquitin-binding proteins play an important role in eukaryotes by translating differently
linked polyubiquitin chains into proper cellular responses. Current knowledge about …

Apicomplexan parasites cause major human disease and food insecurity. They owe their
considerable success to highly specialized cell compartments and structures. These …

Tumor associated inflammation predicts response to immune checkpoint blockade in human
melanoma. Current theories on regulation of inflammation center on anti-tumor T cell …

Existing high-throughput methods to identify RNA-binding proteins (RBPs) are based on
capture of polyadenylated RNAs and cannot recover proteins that interact with …

MSstats is an R package for statistical relative quantification of proteins and peptides in
mass spectrometry-based proteomics. Version 2.0 of MSstats supports label-free and label …

Missing values are a genuine issue in label-free quantitative proteomics. Recent works have
surveyed the different statistical methods to conduct imputation and have compared them on …