P. aeruginosa is still one of the most threatening pathogens responsible for serious hospital-
acquired infections. It is intrinsically resistant to many antimicrobial agents and additional …

Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes a range
of serious infections that are often challenging to treat, as this pathogen can express multiple …

Carbapenem resistance in Gram-negative bacteria has come into sight as a serious global
threat. Carbapenem-resistant Gram-negative pathogens and their main representatives …

Pseudomonas aeruginosa is a common pathogen that is associated with multidrug-resistant
(MDR) and carbapenem-resistant (CR) phenotypes; therefore, we investigated its resistance …

Resistance to antimicrobials and particularly multidrug resistance is one of the greatest
challenges in the health system nowadays. The continual increase in the rates of …

Objectives To describe the pharmacokinetic/pharmacodynamic (PK/PD) behaviour of
continuous infusion (CI) ceftazidime-avibactam and the microbiological outcome in a case …

Introduction: Not enough data exist to inform the optimal duration and type of antimicrobial
therapy against GN infections in critically ill patients. Methods: Narrative review based on a …

Bacterial resistance mechanisms are continuously and rapidly evolving. This is particularly
true for Gram-negative bacteria. Over the last decade, the strategy to develop new β …

Promoting the optimal use of antibiotics through evidence-based recommendations should
be regarded as a crucial step in the global fight against antimicrobial resistance. Within this …

Severe/MDR Gram-negative infections continue to be important infections due to their
impact on patient outcomes, especially in critically ill and immunocompromised hosts. The …