Leveraging semiconducting polymer nanoparticles for combination cancer immunotherapy

J Wu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Cancer immunotherapy has become a promising method for cancer treatment, bringing
hope to advanced cancer patients. However, immune‐related adverse events caused by …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Nanomaterial-based contrast agents

JC Hsu, Z Tang, OE Eremina, AM Sofias… - Nature Reviews …, 2023 - nature.com
Medical imaging, which empowers the detection of physiological and pathological
processes within living subjects, has a vital role in both preclinical and clinical diagnostics …

Exosome‐Inhibiting Polymeric Sonosensitizer for Tumor‐Specific Sonodynamic Immunotherapy

J Wu, J Huang, J Yu, M Xu, J Liu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Combination cancer immunotherapy based on electromagnetic energy and immunotherapy
shows potent anti‐cancer efficacy. However, as a factor that mediates tumor metastasis and …

Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

X Ren, Y Feng, J Guo, H Wang, Q Li, J Yang… - Chemical Society …, 2015 - pubs.rsc.org
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy

J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …