Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlap** and interdigitated …

Skeletal muscle represents the largest body-composition component in humans. In addition
to its primary function in the maintenance of upright posture and the production of …

▪ Abstract Focal adhesions are sites of tight adhesion to the underlying extracellular matrix
developed by cells in culture. They provide a structural link between the actin cytoskeleton …

The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …

Duchenne muscular dystrophy is a fatal neuromuscular disorder affecting around one in
3,500–5,000 male births that is characterized by progressive muscular deterioration. It is …

Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …

Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

The heart is a rhythmic electromechanical pump, the functioning of which depends on action
potential generation and propagation, followed by relaxation and a period of refractoriness …

The dystrophin complex stabilizes the plasma membrane of striated muscle cells. Loss of
function mutations in the genes encoding dystrophin, or the associated proteins, triggers …

The laminins are a family of glycoproteins that provide an integral part of the structural
scaffolding of basement membranes in almost every animal tissue. Each laminin is a …