The life sciences can benefit greatly from imaging technologies that connect microscopic
discoveries with macroscopic observations. One technology uniquely positioned to provide …

Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …

Imaging of small animals has played an indispensable role in preclinical research by
providing high-dimensional physiological, pathological and phenotypic insights with clinical …

Deposits of amyloid-β (Aβ) in the brains of rodents can be analysed by invasive intravital
microscopy on a submillimetre scale, or via whole-brain images from modalities lacking the …

We review the history of photoacoustics from the discovery in 1880 that modulated light
produces acoustic waves to the current time, when the pulsed variant of the discovery is fast …

Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …

Photoacoustic imaging—a hybrid biomedical imaging modality finding its way to clinical
practices. Although the photoacoustic phenomenon was known more than a century back …

Administrating pharmaceutic agents efficiently to achieve the therapeutic effect is the aim of
all drug delivery techniques. Recent drug delivery systems aim to deliver high doses of …

Functional photoacoustic imaging is a promising biological imaging technique that offers
such unique benefits as scalable resolution and imaging depth, as well as the ability to …

Fuelled by innovation, optical microscopy plays a critical role in the life sciences and
medicine, from basic discovery to clinical diagnostics. However, optical microscopy is limited …