The emergent properties of the connected brain

M Thiebaut de Schotten, SJ Forkel - Science, 2022 - science.org
There is more to brain connections than the mere transfer of signals between brain regions.
Behavior and cognition emerge through cortical area interaction. This requires integration …

Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight

JW Vogel, N Corriveau-Lecavalier… - Nature Reviews …, 2023 - nature.com
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Brain–phenotype models fail for individuals who defy sample stereotypes

AS Greene, X Shen, S Noble, C Horien, CA Hahn… - Nature, 2022 - nature.com
Individual differences in brain functional organization track a range of traits, symptoms and
behaviours,,,,,,,,,,–. So far, work modelling linear brain–phenotype relationships has …

Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

J Chen, A Tam, V Kebets, C Orban, LQR Ooi… - Nature …, 2022 - nature.com
How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …

[HTML][HTML] The human connectome project: a retrospective

JS Elam, MF Glasser, MP Harms, SN Sotiropoulos… - NeuroImage, 2021 - Elsevier
Abstract The Human Connectome Project (HCP) was launched in 2010 as an ambitious
effort to accelerate advances in human neuroimaging, particularly for measures of brain …

Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization

S Ryali, Y Zhang, C de Los Angeles, K Supekar… - Proceedings of the …, 2024 - pnas.org
Sex plays a crucial role in human brain development, aging, and the manifestation of
psychiatric and neurological disorders. However, our understanding of sex differences in …

Braingnn: Interpretable brain graph neural network for fmri analysis

X Li, Y Zhou, N Dvornek, M Zhang, S Gao… - Medical Image …, 2021 - Elsevier
Understanding which brain regions are related to a specific neurological disorder or
cognitive stimuli has been an important area of neuroimaging research. We propose …

Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Functional brain networks reflect spatial and temporal autocorrelation

M Shinn, A Hu, L Turner, S Noble, KH Preller, JL Ji… - Nature …, 2023 - nature.com
High-throughput experimental methods in neuroscience have led to an explosion of
techniques for measuring complex interactions and multi-dimensional patterns. However …