Many pharmacologically active compounds are of amphiphilic (or hydrophobic) nature. As a
result, they tend to self-associate and to interact with biological membranes. This review …

Optical spectroscopies have been intensively used to determine partition coefficients by a
plethora of methodologies. The present review is intended to give detailed and useful …

The present study delineates the formulation of niosomes from biocompatible surfactant
Tyloxapol and their potential as drug delivery system for anti-tuberculosis drugs. Drug …

Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of
chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad …

A new, simple procedure for the determination of partition coefficients (P) was developed
based on spectral effects caused upon addition of solutes to spin labeled model lipid …

The lipophilicity of β-adrenoceptor antagonists (RS)-propranolol and (S)-dihydroalprenolol
is characterized in a standardized liposomal partition system at 37° C. Apparent partition …

It has recently been found that Pluronics (block copolymers of ethylene oxide, EO, and
propylene oxide, PO) favor the permeability and accumulation of anthracycline antibiotics …

We examined the effect of uncharged lidocaine on the structure and dynamics of egg
phosphatidylcholine (EPC) membranes at pH 10.5 in order to assess the location of this …

The various stages of the interaction between the detergent Triton X-100 (TTX-100) and
membranes of whole red blood cells (RBC) were investigated in a broad range of detergent …

The detergents, alkyltrimethylammonium bromide, N-alkyl-N, N-dimethyl-3-ammonio-1-
propanesulfonate (zwittergent), alkane sulfonate, alkylsulfate, alkyl-β-d-glucopyranoside …