Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Lipid rafts as a membrane-organizing principle
D Lingwood, K Simons - science, 2010 - science.org
Cell membranes display a tremendous complexity of lipids and proteins designed to perform
the functions cells require. To coordinate these functions, the membrane is able to laterally …
the functions cells require. To coordinate these functions, the membrane is able to laterally …
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
A fundamental feature of cellular plasma membranes (PMs) is an asymmetric lipid
distribution between the bilayer leaflets. However, neither the detailed, comprehensive …
distribution between the bilayer leaflets. However, neither the detailed, comprehensive …
Kinetic control of shape deformations and membrane phase separation inside giant vesicles
A variety of cellular processes use liquid–liquid phase separation (LLPS) to create functional
levels of organization, but the kinetic pathways by which it proceeds remain incompletely …
levels of organization, but the kinetic pathways by which it proceeds remain incompletely …
[HTML][HTML] The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model
FM Goñi - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2014 - Elsevier
The fluid mosaic model of Singer and Nicolson (1972) is a commonly used representation of
the cell membrane structure and dynamics. However a number of features, the result of four …
the cell membrane structure and dynamics. However a number of features, the result of four …
Membrane lipid nanodomains
Lipid membranes can spontaneously organize their components into domains of different
sizes and properties. The organization of membrane lipids into nanodomains might …
sizes and properties. The organization of membrane lipids into nanodomains might …
Liposomes: technologies and analytical applications
A Jesorka, O Orwar - Annu. Rev. Anal. Chem., 2008 - annualreviews.org
Liposomes are structurally and functionally some of the most versatile supramolecular
assemblies in existence. Since the beginning of active research on lipid vesicles in 1965 …
assemblies in existence. Since the beginning of active research on lipid vesicles in 1965 …
[HTML][HTML] Seeing spots: complex phase behavior in simple membranes
Liquid domains in model lipid bilayers are frequently studied as models of raft domains in
cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles …
cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles …
Membrane domains and the “lipid raft” concept
S Sonnino, A Prinetti - Current medicinal chemistry, 2013 - ingentaconnect.com
The bulk structure of biological membranes consists of a bilayer of amphipathic lipids.
According to the fluid mosaic model proposed by Singer and Nicholson, the …
According to the fluid mosaic model proposed by Singer and Nicholson, the …
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes
296a Monday, February 27, 2012 counterparts remains unknown, especially of lipids such
as sphingolipids that, when unlabeled, enter ''raft''domains in model systems, termed …
as sphingolipids that, when unlabeled, enter ''raft''domains in model systems, termed …