Antimicrobial resistance (AMR) is a major global public health threat, which has been largely
driven by the excessive use of antimicrobials. Control measures are urgently needed to slow …

Highlights•Machine learning is increasingly used to predict and understand drug resistance
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …

Background We evaluated the prevalence of transmitted drug resistance (TDR) to integrase
strand-transfer inhibitors (INSTIs) and nucleoside/nucleotide reverse transcriptase inhibitors …

Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …

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Background Infection with human immunodeficiency virus type 1 (HIV) typically results from
transmission of a small and genetically uniform viral population. Following transmission, the …

Objectives The main objective of this analysis was to evaluate the impact of pre‐existing
drug resistance by next‐generation sequencing (NGS) on the risk of treatment failure (TF) of …

Background To assess the prevalence and evolution of transmitted drug resistance (TDR) in
Belgium, a total of 3708 baseline human immunodeficiency virus (HIV)-1 polymerase …

Objectives HIV-1 infection continues to be a significant public health concern,
notwithstanding the expanded utilization of antiretroviral treatment (ART), due to the …

Background: Preexisting drug resistance limits the utility of HIV antiretroviral therapy. Studies
have demonstrated safety and efficacy of bictegravir/emtricitabine/tenofovir alafenamide …