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Soluble epoxide hydrolase: Mechanisms and therapeutic potential in psychiatric and neurological disorders
MM Zhao, JJ Yang… - … in pharmacology (San …, 2025 - pubmed.ncbi.nlm.nih.gov
Soluble epoxide hydrolase (sEH), encoded by the EPHX2 gene, is a critical enzyme
involved in the metabolism of polyunsaturated fatty acids, specifically anti-inflammatory …
involved in the metabolism of polyunsaturated fatty acids, specifically anti-inflammatory …
Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies
J Jarne-Ferrer, J Sánchez, S Codony… - ACS Pharmacology & …, 2025 - ACS Publications
Neuroinflammation is widely recognized as a key pathological hallmark of Alzheimer's
disease (AD). Recently, inhibiting soluble epoxide hydrolase (sEH) has emerged as a …
disease (AD). Recently, inhibiting soluble epoxide hydrolase (sEH) has emerged as a …
[HTML][HTML] Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain
D Babkov, N Eliseeva, K Adzhienko… - International Journal of …, 2024 - mdpi.com
Inhibition of soluble epoxide hydrolase (sEH) is a promising therapeutic strategy for treating
neuropathic pain. These inhibitors effectively reduce diabetic neuropathic pain and …
neuropathic pain. These inhibitors effectively reduce diabetic neuropathic pain and …