Aristolochic acid-associated cancers: a public health risk in need of global action

S Das, S Thakur, M Korenjak, VS Sidorenko… - Nature Reviews …, 2022 - nature.com
Aristolochic acids (AAs) are a group of naturally occurring compounds present in many plant
species of the Aristolochiaceae family. Exposure to AA is a significant risk factor for severe …

A body map of somatic mutagenesis in morphologically normal human tissues

R Li, L Di, J Li, W Fan, Y Liu, W Guo, W Liu, L Liu, Q Li… - Nature, 2021 - nature.com
Somatic mutations that accumulate in normal tissues are associated with ageing and
disease,. Here we performed a comprehensive genomic analysis of 1,737 morphologically …

Macroscopic somatic clonal expansion in morphologically normal human urothelium

R Li, Y Du, Z Chen, D Xu, T Lin, S **, G Wang, Z Liu… - Science, 2020 - science.org
Knowledge of somatic mutation accumulation in normal cells, which is essential for
understanding cancer development and evolution, remains largely lacking. In this study, we …

[HTML][HTML] Identifying clonal origin of multifocal hepatocellular carcinoma and its clinical implications

D ** urothelial carcinoma of the bladder (UCB) in patients treated by
radical nephroureterectomy (RNU) for an upper urinary tract urothelial carcinoma (UTUC) is …