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Gamma-linolenic acid, dihommo-gamma linolenic, eicosanoids and inflammatory processes
Abstract Gamma-linolenic acid (GLA, 18: 3n-6) is an omega-6 (n-6), 18 carbon (18C-)
polyunsaturated fatty acid (PUFA) found in human milk and several botanical seed oils and …
polyunsaturated fatty acid (PUFA) found in human milk and several botanical seed oils and …
Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis
JY Zhang, KSD Kothapalli… - Current Opinion in Clinical …, 2016 - journals.lww.com
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Precision nutrition and omega-3 polyunsaturated fatty acids: A case for personalized supplementation approaches for the prevention and management of human …
Background: Dietary essential omega-6 (n-6) and omega-3 (n-3) 18 carbon (18C-)
polyunsaturated fatty acids (PUFA), linoleic acid (LA) and α-linolenic acid (ALA), can be …
polyunsaturated fatty acids (PUFA), linoleic acid (LA) and α-linolenic acid (ALA), can be …
Selection in Europeans on fatty acid desaturases associated with dietary changes
FADS genes encode fatty acid desaturases that are important for the conversion of short
chain polyunsaturated fatty acids (PUFAs) to long chain fatty acids. Prior studies indicate that …
chain polyunsaturated fatty acids (PUFAs) to long chain fatty acids. Prior studies indicate that …
Identification of sequence variants influencing immunoglobulin levels
S Jonsson, G Sveinbjornsson… - Nature …, 2017 - nature.com
Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a
genome-wide association study of 19,219 individuals, we found 38 new variants and …
genome-wide association study of 19,219 individuals, we found 38 new variants and …
Dietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs
W He, X Liu, Y Feng, H Ding, H Sun, Z Li… - Journal of Animal Science …, 2024 - Springer
Background Cold stress has negative effects on the growth and health of mammals, and has
become a factor restricting livestock development at high latitudes and on plateaus. The gut …
become a factor restricting livestock development at high latitudes and on plateaus. The gut …
Positive Selection on a Regulatory Insertion–Deletion Polymorphism in FADS2 Influences Apparent Endogenous Synthesis of Arachidonic Acid
Long chain polyunsaturated fatty acids (LCPUFA) are bioactive components of membrane
phospholipids and serve as substrates for signaling molecules. LCPUFA can be obtained …
phospholipids and serve as substrates for signaling molecules. LCPUFA can be obtained …
Association of FADS1/2 locus variants and polyunsaturated fatty acids with aortic stenosis
HY Chen, BJ Cairns, AM Small, HA Burr… - JAMA …, 2020 - jamanetwork.com
Importance Aortic stenosis (AS) has no approved medical treatment. Identifying etiological
pathways for AS could identify pharmacological targets. Objective To identify novel genetic …
pathways for AS could identify pharmacological targets. Objective To identify novel genetic …
[HTML][HTML] Inflammatory response to dietary linoleic acid depends on FADS1 genotype
MA Lankinen, A Fauland, B Shimizu, J Ågren… - The American journal of …, 2019 - Elsevier
Background The health benefits of substituting dietary polyunsaturated fatty acids (PUFAs)
for saturated fatty acids are well known. However, limited information exists on how the …
for saturated fatty acids are well known. However, limited information exists on how the …
The impact of fatty acid desaturase genotype on fatty acid status and cardiovascular health in adults
CM O'Neill, AM Minihane - Proceedings of the Nutrition Society, 2017 - cambridge.org
The aim of this review was to determine the impact of the fatty acid desaturase (FADS)
genotype on plasma and tissue concentrations of the long-chain (LC) n-3 PUFA, including …
genotype on plasma and tissue concentrations of the long-chain (LC) n-3 PUFA, including …