[HTML][HTML] The epigenetic link between prenatal adverse environments and neurodevelopmental disorders

M Kundakovic, I Jaric - Genes, 2017 - mdpi.com
Prenatal adverse environments, such as maternal stress, toxicological exposures, and viral
infections, can disrupt normal brain development and contribute to neurodevelopmental …

Stress in utero: prenatal programming of brain plasticity and cognition

J Bock, T Wainstock, K Braun, M Segal - Biological psychiatry, 2015 - Elsevier
Animal studies confirm earlier anecdotal observations in humans to indicate that early life
experience has a profound impact on adult behavior, years after the original experience has …

Genetics of anxiety disorders: Genetic epidemiological and molecular studies in humans

M Shimada‐Sugimoto, T Otowa… - Psychiatry and clinical …, 2015 - Wiley Online Library
This review provides a broad overview of the state of research in the genetics of anxiety
disorders (AD). Genetic epidemiological studies report a moderate level of familial …

Epigenetic programming by stress and glucocorticoids along the human lifespan

AS Zannas, GP Chrousos - Molecular psychiatry, 2017 - nature.com
Psychosocial stress triggers a set of behavioral, neural, hormonal, and molecular responses
that can be a driving force for survival when adaptive and time-limited, but may also …

[HTML][HTML] Early life adversity: lasting consequences for emotional learning

HJ Krugers, JM Arp, H ** brain, both in
humans and rodents. During this time window, exposure to adverse experiences can …

Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness

PW Abbott, SB Gumusoglu, J Bittle… - …, 2018 - Elsevier
Risk for neuropsychiatric disorders is complex and includes an individual's internal genetic
endowment and their environmental experiences and exposures. Embryonic development …

Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases

NC Gassen, GP Chrousos, EB Binder… - … & Biobehavioral Reviews, 2017 - Elsevier
Life stress has been associated with accelerated cellular aging and increased risk for
develo** aging-related diseases; however, the underlying molecular mechanisms remain …

Methylation of serotonin receptor 3A in ADHD, borderline personality, and bipolar disorders: link with severity of the disorders and childhood maltreatment

N Perroud, S Zewdie, L Stenz, W Adouan… - Depression and …, 2016 - Wiley Online Library
Background Serotonin 3A receptor (5‐HT3AR) is associated at the genetic and epigenetic
levels with a variety of psychiatric disorders and interacts with early‐life stress such as …

The serotonin transporter and early life stress: translational perspectives

DJ Houwing, B Buwalda, EA van der Zee… - Frontiers in cellular …, 2017 - frontiersin.org
The interaction between the serotonin transporter (SERT) linked polymorphic region (5-
HTTLPR) and adverse early life stressing (ELS) events is associated with enhanced stress …

Effects of maternal stress and perinatal fluoxetine exposure on behavioral outcomes of adult male offspring

V Kiryanova, SJ Meunier, HA Vecchiarelli, MN Hill… - Neuroscience, 2016 - Elsevier
Women of child-bearing age are the population group at highest risk for depression. In
pregnant women, fluoxetine (Flx) is the most widely prescribed selective serotonin reuptake …