CRISPR-based diagnostics

MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …

Synergizing nanomaterials and artificial intelligence in advanced optical biosensors for precision antimicrobial resistance diagnosis

BA Taha, NM Ahmed, RK Talreja, AJ Haider… - ACS Synthetic …, 2024 - ACS Publications
Antimicrobial resistance (AMR) poses a critical global One Health concern, ensuing from
unintentional and continuous exposure to antibiotics, as well as challenges in accurate …

CRISPR-Cas13a system: A novel tool for molecular diagnostics

L Zhao, M Qiu, X Li, J Yang, J Li - Frontiers in Microbiology, 2022 - frontiersin.org
The clustered regularly interspaced short palindromic repeats (CRISPR) system is a natural
adaptive immune system of prokaryotes. The CRISPR-Cas system is currently divided into …

CRISPR-based biosensors for pathogenic biosafety

H Yang, R Ledesma-Amaro, H Gao, Y Ren… - Biosensors and …, 2023 - Elsevier
Pathogenic biosafety is a worldwide concern. Tools for analyzing pathogenic biosafety, that
are precise, rapid and field-deployable, are highly demanded. Recently developed …

CRISPR-Cas-mediated diagnostics

L Li, G Shen, M Wu, J Jiang, Q ** world. Effective diagnostics are urgently needed for improved control of this …

A suite of PCR-LwCas13a assays for detection and genoty** of Treponema pallidum in clinical samples

W Chen, H Luo, L Zeng, Y Pan, JB Parr, Y Jiang… - Nature …, 2022 - nature.com
The performance of commonly used assays for diagnosis of syphilis varies considerably
depending on stage of infection and sample type. In response to the need for improved …